Deep Dives

Regeneron was founded in 1988 by Dr. Leonard S Schleifer. Dr. Schelifer shared, that the name Regeneron came from “Regenerating neurons, with the word “gene” in the middle”.  The origin of the name further explains that the initial focus of the company was neurobiology. Then in 1990 following the publication

Founded in 2002, Alnylam has led the commercialization of RNAi. However, the company has faced multiple battles on its way here. After the initial hype of RNA technologies faded in the 2010s, many RNAi companies faced a downturn as the industry quickly lost confidence in the ability to commercialize RNA-based

Sarepta Therapeutics (NASDAQ:SRPT) was founded by Marwan Fawaz in 1980 with the mission of developing precision genetic medicines for the treatment of rare neuromuscular diseases. Fast forward to 2022 and Sarepta Therapeutics is a pioneer in Duchenne muscular dystrophy (DMD) therapy with three FDA-approved RNA therapies to treat this

History of Vertex Vertex was founded in 1989 by Joshua Boger and Kevin J. Kinsella to "transform the way serious diseases are treated”. The company's initial successes in anti-viral therapies (HIV and Hepatitis C) were short-lived due to stiff competition. This forced the company to pivot to survive, but like

We examine CRISPR Therapeutics to understand what it is working on and if it has the potential to shape the future of healthcare. This is a story of how humans can learn from nature. In recent years several CRISPR-related companies have gone public. There has also been a plethora of

What is proteomics? During the expression of a protein-coding gene, information flows from DNA → RNA →protein. This directional flow of information is known as the central dogma of molecular biology. (Learn more about DNA and RNA in our previous articles.) Proteomics, in simple terms, is the study of proteins. This